PROTAC SMARCA2/4-degrader-6 [CAS 2568277-87-0]

PROTAC SMARCA2/4-degrader-6 (compound I-438) is a SMARCA2/4 degrader. PROTAC SMARCA2/4-degrader-6 has the potential for the research of cancer. (Pink: SMARCA2/4 ligand, ; Black: linker (HY-W006635) ; Blue: VHL ligand (HY-112078) ).

[2568277-87-0]

C50H61N11O5S

928.16

NC1=C(C=C(C2=C(C=CC=C2)O)N=N1)N3CC4N(C5=NC=C([C@@H]6CC[C@H](CC6)C(N[C@@H](C(C)(C)C)C(N7[C@@H](C[C@H](C7)O)C(N[C@H](C8=CC=C(C9=C(N=CS9)C)C=C8)C)=O)=O)=O)C=N5)C(CC4)C3

Epigenetic Reader Domain; PROTACs

Room temperature