PROTAC α-synuclein degrader 3 [CAS 2412273-77-7]

PROTAC α-synuclein degrader 3 (Compound 5) is a selective α-synuclein PROTAC degrader. PROTAC α-synuclein degrader 3 can promote the ubiquitination and degradation of α-synuclein. PROTAC α-synuclein degrader 3 can be used for Parkinson's disease research (Pink: target protein ligand ; Black: linker; HY-133302; Blue: E3 ligase VHL ligand (HY-112078) ).

[2412273-77-7]

C51H68N6O11S2

1005.25

CNC(C=C1)=CC=C1C2=NC3=C(S2)C=C(OCCOCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@H](C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)C[C@@H](O)C4)=O)=O)C=C3

PROTACs; α-synuclein

α-synuclein

99.61

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, sealed storage, away from moisture)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335