Name: PROTAC TTK degrader-1 [CAS 2953426-43-0]
Brand: QuantiMol
SKU: QM-0148025-01
Price: 612.54 GBP
Availability: InStock

Product Details

Description
PROTAC TTK degrader-1 is a potent TTK (threonine tyrosine kinase) PROTAC degrader, with DC50 values of 1.7 and 5.8 nM in COLO-205 and HCT-116 cell, respectively. PROTAC TTK degrader-1 exhibits target degradation and anticancer efficacy in a xenograft mouse model of COLO-205 human colorectal cancer cells[1].
CAS Number
[2953426-43-0]
Molecular Formula
C47H53N9O7
Molecular Weight
855.98
Smiles
O=C1N(C2=NC(NC3=C(C=C(C=C3)N4CCN(CC4)C(CCCC#CC5=CC=C6C(N(CC6=C5)C7C(NC(CC7)=O)=O)=O)=O)OC)=NC=C2C(C)=C1)[C@@H]8CC[C@@H](CC8)NC(CC)=O
Target
PROTACs
Purity
98.01
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, protect from light)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0148025-01	1 mgQM-0148025-01 £612.54/ea	£0.00	Quantity	£612.54/ea	£0.00

5 mgQM-0148025-02	5 mgQM-0148025-02 £1,455.76/ea	£0.00	Quantity	£1,455.76/ea	£0.00

10 mM - 1 mLQM-0148025-03	10 mM - 1 mLQM-0148025-03 £2,295.32/ea	£0.00	Quantity	£2,295.32/ea	£0.00

10 mgQM-0148025-04	10 mgQM-0148025-04 £2,435.05/ea	£0.00	Quantity	£2,435.05/ea	£0.00

25 mgQM-0148025-05	25 mgQM-0148025-05 £4,820.09/ea	£0.00	Quantity	£4,820.09/ea	£0.00

50 mgQM-0148025-06	50 mgQM-0148025-06 £7,681.41/ea	£0.00	Quantity	£7,681.41/ea	£0.00

100 mgQM-0148025-07	100 mgQM-0148025-07 £11,497.73/ea	£0.00	Quantity	£11,497.73/ea	£0.00

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PROTAC TTK degrader-1 [CAS 2953426-43-0]

PROTAC TTK degrader-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.