Protriptyline [CAS 438-60-8]

Protriptyline is a potent tricyclic antidepressant (TCA) . Protriptyline inhibits AChE activity with an IC50 value of 0.06 mM and inhibits Aβ self-assembly. Protriptyline can be used for the study of depression and Alzheimers disease[1][2][3].

[438-60-8]

C19H21N

263.38

CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13

Amyloid-β; Cholinesterase (ChE)

AChE

10 mM in DMSO

Room temperature

H315-H319-H320

P264-P280-P302+P352-P305+P351+P338-P362