PS372424 [CAS 914291-61-5]

PS372424, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity. PS372424 prevents human T-cell migration in a humanized model of arthritic inflammation[1][2].

[914291-61-5]

C33H44N6O4

588.74

O=C([C@H]1N(C(CCC(C2=CC=CC=C2)=O)=O)CC3=C(C=CC=C3)C1)N[C@H](C(NCC4CCCCC4)=O)CCCNC(N)=N

CXCR

CXCR3

98

10 mM in DMSO

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H301

P264-P270-P330-P405-P501