PSB 0474 [CAS 917567-60-3]

PSB 0474 (3-phenacyl-UDP) is a selective and potent P2Y6 receptor agonist with an EC50 of 70 nM[1]. PSB 0474 inhibits cell proliferation, increases NO release in astrocytes and microglia cells. PSB 0474 induces astrocytes apoptosis[2].

[917567-60-3]

C17H20N2O13P2

522.29

O[C@H]([C@@H]1O)[C@@](N(C=CC2=O)C(N2CC(C3=CC=CC=C3)=O)=O)([H])O[C@@H]1CO[P](O[P](O)(O)=O)(O)=O

Apoptosis; P2Y Receptor

P2Y6 Receptor

10 mM in DMSO

Room temperature