PX20606 [CAS 1268245-19-7]

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SKU:QM-0079330

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Product Details

Description
PX20606 is an orally active agonist for farnesoid X receptor (FXR), with EC50 220 nM (mFXR) and 50 nM (hFXR), measured by Gal4-FXR assay. PX20606 induces the expression of tumor suppressor gene NDRG2, inhibits the tumor growth and metastasis in mouse HCC model. PX20606 exhibits hepatoprotective efficacy[1].
CAS Number
[1268245-19-7]
Molecular Formula
C29H22Cl3NO4
Molecular Weight
554.85
Smiles
O=C(O)C(C=C1)=CC=C1C(C2)C2C3=CC=C(OCC4=C(C5CC5)ON=C4C6=C(Cl)C=CC=C6Cl)C=C3Cl
Target
FXR
Shipping Conditions
Room temperature

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PX20606 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.