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PYZD-4409 [CAS 423148-78-1]

PYZD-4409 [CAS 423148-78-1]

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SKU:QM-0144241-01

£129.63 GBP
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  • Description

    PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay) . PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells[1].

  • CAS Number

    [423148-78-1]

  • Molecular Formula

    C14H7ClFN3O5

  • Molecular Weight

    351.67

  • Smiles

    FC1=CC=C(N2C(/C(C(N2)=O)=C\C3=CC=C([N+]([O-])=O)O3)=O)C=C1Cl

  • Target

    E1/E2/E3 Enzyme

  • Purity

    98

  • Solubility

    DMSO : ≥ 35 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H301, H315, H319, H335

  • Precautions

    H301, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0144241-01
5 mgQM-0144241-01
£129.63/ea
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10 mM - 1 mLQM-0144241-02
10 mM - 1 mLQM-0144241-02
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10 mgQM-0144241-03
10 mgQM-0144241-03
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25 mgQM-0144241-04
25 mgQM-0144241-04
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50 mgQM-0144241-05
50 mgQM-0144241-05
£614.98/ea
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£614.98/ea £0.00
100 mgQM-0144241-06
100 mgQM-0144241-06
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PYZD-4409 [CAS 423148-78-1]

PYZD-4409 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.