QL47B [CAS 1579278-92-4]

QL47B, a biotinylated analogue of QL47 , is a potent inhibitor of BTK, with an IC50 value of 1.3 μM. QL47B has anti-tumor activity[1].

[1579278-92-4]

C46H55N9O7S

878.05

O=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CN(C)N=C4)C=C32)C5=CC=C6C(N(C(/C=C/CNCCOCCOCCOCCNC(CCCC[C@H]7[C@](NC(N8)=O)([H])[C@]8([H])CS7)=O)=O)CC6)=C5

Btk

10 mM in DMSO

Room temperature