Quinapril [CAS 85441-61-8]

Quinapril is a potent, orally active, non-peptide and nonsulfhydryl inhibitor of angiotensin-converting enzyme (ACE) . Quinapril specifically interrupts the conversion of angiotensin I to angiotensin II in both plasma and tissue. Quinapril is enzymatically hydrolyzed to a pharmacologically active diacid form quinaprilat. Quinapril is efficacious in hypertensive models[1].

[85441-61-8]

C25H30N2O5

438.52

O=C([C@H]1N(C([C@@H](N[C@H](C(OCC)=O)CCC2=CC=CC=C2)C)=O)CC3=C(C=CC=C3)C1)O

Angiotensin-converting Enzyme (ACE)

Room temperature

H302-H312-H332

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501