(R) -8-Azido-2- (Fmoc-amino) octanoic acid [CAS 1191429-18-1]
(R) -8-Azido-2- (Fmoc-amino) octanoic acid [CAS 1191429-18-1]
SKU:QM-0061664
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Product Details
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Description
(R) -8-Azido-2- (Fmoc-amino) octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. (R) -8-Azido-2- (Fmoc-amino) octanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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CAS Number
[1191429-18-1]
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Molecular Formula
C23H26N4O4
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Molecular Weight
422.48
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Smiles
OC([C@@H](CCCCCCN=[N+]=[N-])NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O
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Target
ADC Linker
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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(R) -8-Azido-2- (Fmoc-amino) octanoic acid [CAS 1191429-18-1]
(R) -8-Azido-2- (Fmoc-amino) octanoic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.