Skip to product information
1 of 1

(R) -Colchicine [CAS 75520-89-7]

(R) -Colchicine [CAS 75520-89-7]

Size

SKU:QM-0053617

Price on request
Quantity

Request quote or documents

View full details
  • Description

    (R) -Colchicine is the R-isomer of Colchicine. Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID) -induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research[1][2][3][4][5].

  • CAS Number

    [75520-89-7]

  • Molecular Formula

    C22H25NO6

  • Molecular Weight

    399.44

  • Smiles

    COC1=C2C(C([C@@H](CCC2=CC(OC)=C1OC)NC(C)=O)=C3)=CC=C(OC)C3=O

  • Target

    Apoptosis; Autophagy; Drug Isomer; Microtubule/Tubulin; NOD-like Receptor (NLR)

  • Shipping Conditions

    Room temperature

Your cart
Variant Variant total Quantity Price Variant total
1 EachQM-0053617
1 EachQM-0053617
Regular price
£0.00
Sale price
£0.00/ea
£0.00
Regular price
£0.00
Sale price
£0.00/ea
£0.00

(R) -Colchicine [CAS 75520-89-7]

(R) -Colchicine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.