(R) -MK-8353 [CAS 2748457-30-7]

(R) -MK-8353 ((R) -SCH900353) is the R-enantiomer of MK-8353. MK-8353 (SCH900353) is a potent, selective and orally active ERK1 and ERK2 inhibitor with IC50s of 23.0 nM and 8.8 nM, respectively[1].

[2748457-30-7]

C37H41N9O3S

691.84

O=C([C@]1(SC)CN(CC(N2CC=C(C3=CC=C(C4=NN(C)C=N4)C=C3)CC2)=O)CC1)NC5=CC6=C(NN=C6C7=CC=C(OC(C)C)N=C7)C=C5

ERK

96.59

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature