(R, R) -THC [CAS 221368-54-3]

(R, R) -THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively. (R, R) -THC has higher relative binding affinity for ERβ than ERα with the values of 25 and 3.6[1].

[221368-54-3]

C22H24O2

320.42

OC(C=C1C[C@H]2CC)=CC=C1C3=C2C4=C(C=C(O)C=C4)C[C@H]3CC

Estrogen Receptor/ERR

ERα; ERβ

99

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice