(R, S) -Ivosidenib [CAS 2070009-31-1]

(R, S) -Ivosidenib ((R, S) -AG-120) is a less active enantiomer of ivosidenib (AG-120) . Ivosidenib can be used in the research of IDH1 mutant cancers[1].

[2070009-31-1]

C28H22ClF3N6O3

582.96

FC1(F)CC(NC([C@H](N(C2=CC(F)=CN=C2)C([C@@H](N3C4=NC=CC(C#N)=C4)CCC3=O)=O)C5=CC=CC=C5Cl)=O)C1

Isocitrate Dehydrogenase (IDH)

98.49

DMSO : 3.33 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H315, H317, H319, H335

H315, H317, H319, H335