(R) -Thionisoxetine [CAS 163059-33-4]

(R) -Thionisoxetine is a potent and selective inhibitor of central and peripheral norepinephrine (NE) uptake. (R) -thionisoxetine prevented hypothalamic NE depletion by 6-hydroxydopamine with an ED50 of 0.21 mg/kg. (R) -Thionisoxetine can be used for the research of a variety of diseases including depression and urinary incontinence[1].

[163059-33-4]

C17H21NOS

287.42

CSC1=CC=CC=C1O[C@@H](C2=CC=CC=C2)CCNC

Dopamine Receptor

10 mM in DMSO

Room temperature