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R59949 [CAS 120166-69-0]

R59949 [CAS 120166-69-0]

Size

QM-0112993-01

£72.61 GBP
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Product Details

  • Description

    R59949 is a pan diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM. R59949 strongly inhibits the activity of type I DGK α and γ and moderately attenuates the activity of type II DGK θ and κ. R59949 activates protein kinase C (PKC) by enhancing the levels of the endogenous ligand diacyl glycerol[1][2][3].

  • CAS Number

    [120166-69-0]

  • Molecular Formula

    C28H25F2N3OS

  • Molecular Weight

    489.58

  • Smiles

    O=C1N(CCN2CC/C(CC2)=C(C3=CC=C(F)C=C3)\C4=CC=C(F)C=C4)C(NC5=C1C=CC=C5)=S

  • Target

    PKC

  • Concentration

    10mM

  • Purity

    99.08

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C (Powder, stored under nitrogen)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302, H315, H319

  • Precautions

    H302, H315, H319
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Variant Variant total Quantity Price Variant total
1 mgQM-0112993-01
1 mgQM-0112993-01
£72.61/ea		 £0.00
£72.61/ea £0.00
5 mgQM-0112993-02
5 mgQM-0112993-02
£146.50/ea		 £0.00
£146.50/ea £0.00
10 mM - 1 mLQM-0112993-03
10 mM - 1 mLQM-0112993-03
£192.16/ea		 £0.00
£192.16/ea £0.00
10 mgQM-0112993-04
10 mgQM-0112993-04
£278.42/ea		 £0.00
£278.42/ea £0.00
25 mgQM-0112993-05
25 mgQM-0112993-05
£527.50/ea		 £0.00
£527.50/ea £0.00
50 mgQM-0112993-06
50 mgQM-0112993-06
£768.07/ea		 £0.00
£768.07/ea £0.00
100 mgQM-0112993-07
100 mgQM-0112993-07
£1,126.49/ea		 £0.00
£1,126.49/ea £0.00
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R59949 [CAS 120166-69-0]

R59949 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.