Rabeprazole-d4 (potassium)

Rabeprazole-d4 potassium is deuterated labeled Rabeprazole potassium. Rabeprazole (LY307640) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an b>IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].

C18H16D4KN3O3S

401.56

O=S(C1=NC2=C([2H])C([2H])=C([2H])C([2H])=C2N1[K])CC3=NC=CC(OCCCOC)=C3C

Apoptosis; Bacterial; Isotope-Labeled Compounds; Proton Pump

10 mM in DMSO

Room temperature