(Rac) -AB-423 [CAS 422547-55-5]

(Rac) -AB-423 (DVR-23) is an anti-HBV candidate compound with promising anti-HBV activity. (Rac) -AB-423 showed no induction of CYP1A2, CYP3A4, or CYP2B6 enzyme activity at high concentrations. (Rac) -AB-423 exhibited desirable pharmacokinetic properties, enabling good systemic exposure and high oral bioavailability. (Rac) -AB-423 achieved more than 2 log viral load reduction in the hydrodynamic injection (HDI) HBV mouse model[1].

[422547-55-5]

C17H17F3N2O3S

386.39

O=C(NC1=CC=C(F)C(F)=C1)C2=CC(S(=O)(NC(C)CC)=O)=CC=C2F

HBV

Room temperature