(Rac) -EBET-1055 [CAS 3031540-65-2]

(Rac) -EBET-1055 is the racemate of EBET-1055. EBET-1055 is a bromodomain and extra-terminal (BET) PROTAC degrader. EBET-1055 effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC). EBET-1055 also simultaneously modulates cancer-associated fibroblast (CAF) activity, upregulating all reporter gene activities in organoid co-cultures[1].

[3031540-65-2]

C51H54N8O9

923.02

OCC(OC1CC1)(C2=CC=CC=C2)C3=NC(N4CCC(CN5CCN(C(COC6=CC=CC(C(N7C8CCC(NC8=O)=O)=O)=C6C7=O)=O)CC5)CC4)=NC9=CC=C(C(C=C%10C)=CN(C)C%10=O)C=C93

Epigenetic Reader Domain; PROTACs

97.17

DMSO : 100 mg/mL (ultrasonic)

-20°C (Powder, protect from light, stored under nitrogen)

Blue Ice