(Rac) -Finerenone [CAS 1050477-27-4]

(Rac) -Finerenone ((Rac) -BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM) . Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold) [1].

[1050477-27-4]

C21H22N4O3

378.42

N#CC(C=C1OC)=CC=C1C2C3=C(C(C)=CN=C3OCC)NC(C)=C2C(N)=O

Mineralocorticoid Receptor

10mM

99.66

DMSO : 62.5 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H315-H319

P264-P280-P302+P352-P362+P364