(Rac) -GSK-3484862 [CAS 2170136-02-2]
(Rac) -GSK-3484862 [CAS 2170136-02-2]
SKU:QM-0144966-01
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Product Details
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Description
(Rac) -GSK-3484862 is the isomer of GSK-3484862 , and can be used as an experimental control. GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer. GSK-3484862 mediates dramatic demethylation in murine embryonic stem cells with minimal non-specific toxicity[1][2].
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CAS Number
[2170136-02-2]
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Molecular Formula
C19H19N5OS
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Molecular Weight
365.45
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Smiles
O=C(N)C(SC1=NC(N(C)C)=C(C#N)C(CC)=C1C#N)C2=CC=CC=C2
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Target
DNA Methyltransferase
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Purity
99.43
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Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H312, H315, H319, H332, H335
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Precautions
H302, H312, H315, H319, H332, H335
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(Rac) -GSK-3484862 [CAS 2170136-02-2]
(Rac) -GSK-3484862 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.