(Rac) -Rhododendrol ((Rac) -Betuligenol) is an aromatic compound with pro-oxidant activity. (Rac) -Rhododendrol may be useful in the suppression of liver diseases. (Rac) -Rhododendrol can be toxic to melanocytes, leading to cell death. The metabolite of (Rac) -Rhododendrol, RD-quinone, is cytotoxic and causes enzyme inactivation and endoplasmic reticulum stress by binding to thiol proteins. (Rac) -Rhododendrol-derived melanin exhibits potent pro-oxidant activity and may cause oxidative stress[1].