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RAF mutant-IN-1 [CAS 2340020-82-6]
RAF mutant-IN-1 [CAS 2340020-82-6]
SKU:QM-0060820
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Product Details
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Description
RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].
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CAS Number
[2340020-82-6]
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Molecular Formula
C23H18Cl3FN6O2S
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Molecular Weight
567.85
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Smiles
O=C(C1=CSC2=C(N)N=CN=C21)NC3=C(C)C=CC4=C3C=CN=C4NC5=CC=C(O)C(Cl)=C5F.[H]Cl.[H]Cl
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Target
Raf
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Isoform
B-Raf; C-Raf
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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RAF mutant-IN-1 [CAS 2340020-82-6]
RAF mutant-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.