Rafoxanide [CAS 22662-39-1]
Rafoxanide [CAS 22662-39-1]
SKU:QM-0154781-01
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Product Details
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Description
Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein, which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research[1][2][3].
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CAS Number
[22662-39-1]
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Molecular Formula
C19H11Cl2I2NO3
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Molecular Weight
626.01
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Smiles
O=C(NC1=CC=C(OC2=CC=C(Cl)C=C2)C(Cl)=C1)C3=CC(I)=CC(I)=C3O
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Target
Apoptosis; Oxidative Phosphorylation; p38 MAPK; Parasite; Raf
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Isoform
Schistosome
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Purity
98.6
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Solubility
DMSO : ≥ 31 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H413
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Precautions
H302, H413
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Rafoxanide [CAS 22662-39-1]
Rafoxanide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.