RB-07-16

RB-07-16 is a C6-PyraP-BP inhibitor of human geranylammate pyrophosphate synthase (hGGPPS) . RB-07-16 has antitumor activity[1].

C21H19F3N6O7P2

586.35

CN1N=CC2=C1N=C(C3=CC=CC(C(NC4=CC=C(C(F)(F)F)C=C4)=O)=C3)N=C2NC(P(O)(O)=O)P(O)(O)=O

Apoptosis

10 mM in DMSO

Room temperature