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RBN012811 [CAS 2569517-30-0]

RBN012811 [CAS 2569517-30-0]

Size

QM-0011713-01

£1,523.80 GBP
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Product Details

  • Description

    RBN012811 is a selectively PARP14 PROTAC degrader with a DC50 of 5 nM in KYSE-270 cells. RBN012811 significantly decreases IL-10 expression in IL-4 stimulated macrophages[1]. Pink: PARP14 ligand ; Blue: CRBN ligase ligand (HY-10984) ; Black: linker

  • CAS Number

    [2569517-30-0]

  • Molecular Formula

    C40H49FN8O6S

  • Molecular Weight

    788.93

  • Smiles

    O=C1N=C(CSC2CCN(CC2)CC(NCCCCCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)NC6=CC(NC7CCCC7)=CC(F)=C16

  • Target

    Interleukin Related; PARP; PROTACs

  • Isoform

    IL-10; PARP14

  • Purity

    98.79

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0011713-01
5 mgQM-0011713-01
£1,091.70
£1,523.80/ea
 £0.00
£1,091.70
£1,523.80/ea
 £0.00
10 mgQM-0011713-02
10 mgQM-0011713-02
£1,812.60
£2,497.01/ea
 £0.00
£1,812.60
£2,497.01/ea
 £0.00
25 mgQM-0011713-03
25 mgQM-0011713-03
£3,263.40
£4,455.59/ea
 £0.00
£3,263.40
£4,455.59/ea
 £0.00
50 mgQM-0011713-04
50 mgQM-0011713-04
£4,895.10
£6,658.39/ea
 £0.00
£4,895.10
£6,658.39/ea
 £0.00
100 mgQM-0011713-05
100 mgQM-0011713-05
£6,852.60
£9,301.01/ea
 £0.00
£6,852.60
£9,301.01/ea
 £0.00
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RBN012811 [CAS 2569517-30-0]

RBN012811 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.