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Regorafenib-13C, d3
Regorafenib-13C, d3
SKU:QM-0083205-01
Price on request
Quantity
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Product Details
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Description
Regorafenib-13C, d3 is the 13C- and deuterium labeled Regorafenib. Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively.
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Molecular Formula
C20 13CH12D3ClF4N4O3
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Molecular Weight
486.83
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Smiles
O=C(N[13C]([2H])([2H])[2H])C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=C1
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Target
Autophagy; PDGFR; Raf; RET; VEGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Regorafenib-13C, d3
Regorafenib-13C, d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.