Rel-Avibactam (sodium) [CAS 1383814-68-3]

Ent-Avibactam (NXL-104) sodium is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime , rel-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC50 value of rel-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid (HY-A0256) and Ticarcillin (HY-139805), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes[1][2].

[1383814-68-3]

C7H10N3NaO6S

287.23

NC([C@@H]1[N@]2C(N([C@](CC1)([H])C2)OS(=O)(O[Na])=O)=O)=O

Bacterial; Beta-lactamase

Room temperature