Relamorelin (acetate) [CAS 1809080-14-5]

Relamorelin (RM-131) acetate, a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a Ki of 0.42 nM for GHS-1a receptor. Relamorelin acetate is centrally penetrant. Relamorelin acetate increases growth hormone levels and accelerates gastric emptying. Relamorelin acetate has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research[1][2][3][4][5].

[1809080-14-5]

C45H54N8O7S

851.02

CC(O)=O.O=C(C1CCNCC1)N[C@H](CC2=CSC3=CC=CC=C23)C(N[C@@H](C(N[C@@H](CC4=CC=CC=C4)C(NC5(CCNCC5)C(N)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O

GHSR

10 mM in DMSO

Room temperature