Rev 2’-O-MOE-C (Bz) -5’-amidite

Rev 2’-O-MOE-C (Bz) -5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

C49H58N5O10P

907.99

O=C1N=C(NC(C2=CC=CC=C2)=O)C=CN1[C@@H]3O[C@@H]([C@H]([C@H]3OCCOC)OC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)COP(N(C(C)C)C(C)C)OCCC#N

Nucleoside Antimetabolite/Analog

10 mM in DMSO

Room temperature