Name: RGB-286638 [CAS 784210-87-3]
Brand: QuantiMol
SKU: QM-0151599-01
Price: 188.51 GBP
Availability: InStock

Product Details

Description
RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM.
CAS Number
[784210-87-3]
Molecular Formula
C29H37Cl2N7O4
Molecular Weight
618.55
Smiles
O=C(NN1CCOCC1)NC2=CC=CC(C3=C4C(C5=CC=C(CN6CCN(CCOC)CC6)C=C5)=NN3)=C2C4=O.[H]Cl.[H]Cl
Target
CDK; GSK-3; JAK; MEK
Isoform
CDK1; CDK2; CDK3; CDK4; CDK5; CDK6; CDK7; CDK9; GSK-3β; JAK2; MEK1
Purity
99.7
Solubility
DMSO : ≥ 150 mg/mL|H2O : 25 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0151599-01	5 mgQM-0151599-01 £188.51/ea	£0.00	Quantity	£188.51/ea	£0.00

10 mM - 1 mLQM-0151599-02	10 mM - 1 mLQM-0151599-02 £238.32/ea	£0.00	Quantity	£238.32/ea	£0.00

10 mgQM-0151599-03	10 mgQM-0151599-03 £275.99/ea	£0.00	Quantity	£275.99/ea	£0.00

25 mgQM-0151599-04	25 mgQM-0151599-04 £476.46/ea	£0.00	Quantity	£476.46/ea	£0.00

50 mgQM-0151599-05	50 mgQM-0151599-05 £690.30/ea	£0.00	Quantity	£690.30/ea	£0.00

100 mgQM-0151599-06	100 mgQM-0151599-06 £940.60/ea	£0.00	Quantity	£940.60/ea	£0.00

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RGB-286638 [CAS 784210-87-3]

RGB-286638 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.