RGD peptide (GRGDNP) (TFA)

RGD peptide (GRGDNP) TFA is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) TFA competitively inhibits α5β1 binding with extracellular matrice (ECM) . RGD peptide (GRGDNP) TFA promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) TFA plays an important role in cell adhesion, migration, growth, and differentiation[1][2][3].

C25H39F3N10O12

728.63

O=C(O)[C@H]1N(C([C@H](CC(N)=O)NC([C@H](CC(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC(CN)=O)=O)=O)=O)=O)CCC1.OC(C(F)(F)F)=O

Apoptosis; Caspase; Integrin

Caspase 3; α5β1

99.94

DMSO : ≥ 50 mg/mL|H2O : ≥ 50 mg/mL

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice