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Ribociclib [CAS 1211441-98-3]
Ribociclib [CAS 1211441-98-3]
SKU:QM-0152381-01
£108.25 GBP
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Product Details
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Description
RRibociclib (LEE011) is an ATP-competitive and orally active CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1][1].
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CAS Number
[1211441-98-3]
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Molecular Formula
C23H30N8O
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Molecular Weight
434.54
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Smiles
O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5
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Target
CDK
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Isoform
CDK4; CDK6
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Purity
99.94
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Solubility
DMSO : 6.25 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Ribociclib [CAS 1211441-98-3]
Ribociclib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.