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Ribociclib-d6 (hydrochloride)
Ribociclib-d6 (hydrochloride)
SKU:QM-0152384-01
£426.65 GBP
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Product Details
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Description
Ribociclib-d6 (LEE011-d6) hydrochloride is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1].
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Molecular Formula
C23H25D6ClN8O
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Molecular Weight
477.04
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Smiles
O=C(C1=CC2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5)N(C([2H])([2H])[2H])C([2H])([2H])[2H].Cl
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Target
CDK; Isotope-Labeled Compounds
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Purity
98.37
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Solubility
DMSO : 100mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301, H315, H319, H372, H400
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Precautions
H301, H315, H319, H372, H400
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Ribociclib-d6 (hydrochloride)
Ribociclib-d6 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.