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Ribociclib-d8 [CAS 2167898-24-8]
Ribociclib-d8 [CAS 2167898-24-8]
SKU:QM-0152386-01
£111.63 GBP
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Product Details
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Description
Ribociclib-d8 is the deuterium labeled Ribociclib[1]. Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[2].
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CAS Number
[2167898-24-8]
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Molecular Formula
C23H22D8N8O
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Molecular Weight
442.59
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Smiles
CN(C)C(C(N(C1CCCC1)C2=N3)=CC2=CN=C3NC4=CC=C(N5C([2H])([2H])C([2H])([2H])NC([2H])([2H])C5([2H])[2H])C=N4)=O
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Target
CDK
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Purity
99.23
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Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301, H315, H319, H372, H400
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Precautions
H301, H315, H319, H372, H400
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Ribociclib-d8 [CAS 2167898-24-8]
Ribociclib-d8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.