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Ribociclib hydrochloride [CAS 1211443-80-9]
Ribociclib hydrochloride [CAS 1211443-80-9]
SKU:QM-0152383-01
£117.25 GBP
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Product Details
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Description
Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.
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CAS Number
[1211443-80-9]
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Molecular Formula
C23H31ClN8O
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Molecular Weight
471
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Smiles
O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.Cl
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Target
CDK
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Isoform
CDK4; CDK6
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Purity
99.95
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Solubility
DMSO : 7.69 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301, H315, H319, H372, H400
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Precautions
H301, H315, H319, H372, H400
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Ribociclib hydrochloride [CAS 1211443-80-9]
Ribociclib hydrochloride is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.