1
/
of
1
Ribociclib succinate [CAS 1374639-75-4]
Ribociclib succinate [CAS 1374639-75-4]
SKU:QM-0152385-01
£94.75 GBP
Quantity
Couldn't load pickup availability
Request quote or documents
![Ribociclib succinate [CAS 1374639-75-4]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.
-
CAS Number
[1374639-75-4]
-
Molecular Formula
C27H36N8O5
-
Molecular Weight
552.63
-
Smiles
O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.OC(CCC(O)=O)=O
-
Target
CDK
-
Isoform
CDK4; CDK6
-
Concentration
10mM
-
Purity
99.93
-
Solubility
DMSO : 9.38 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 4.17 mg/mL (ultrasonic; warming; heat to 60°C)
-
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
-
Shipping Conditions
Room Temperature
-
Hazard Statement
H301, H315, H319, H372, H400
-
Precautions
H301, H315, H319, H372, H400
Related Products
- QM-0086965-01 Sterile 10 mM Histidine, pH 5.5 buffer
- QM-0162455-01 L-Methionine-13C, d3 [CAS 73488-65-0]
- QM-0009933-01 L-Histidine buffer, Sterile
- QM-0183109-01 ε-Poly-L-lysine (hydrochloride) (MV 2000-5000)
- QM-0131878-01 ε-Poly-L-lysine (MW 3800-4200) [CAS 28211-04-3]
- QM-0067179 γ-L-Glutamyl-S-allyl-L-cysteine [CAS 1299925-32-8]
- QM-0048489-01 β-N-methylamino-L-alanine (hydrochloride) (Standard) [CAS 16012-55-8]
- QM-0025942-01 Valylleucine (TFA) [CAS 27530-02-5]
- QM-0024513 γ-Glutamylornithine (Standard) [CAS 56523-61-6]
- QM-0024512 β-Lysine [CAS 4299-56-3]
Other industry favorites
- QM-0086965-01 Sterile 10 mM Histidine, pH 5.5 buffer
- QM-0162455-01 L-Methionine-13C, d3 [CAS 73488-65-0]
- QM-0205375-01 γ-Glutamyl-S-allylcysteine [CAS 91216-95-4]
- QM-0204930-01 α-Methyl-DL-aspartic acid [CAS 2792-66-7]
- QM-0161381-01 β-1,3-N-Acetylglucosaminyltransferase 4
- QM-0162316-01 β-Alanine-15N [CAS 204451-53-6]
- QM-0013113 β-Hydroxybutyrate methionine
- QM-0005220-01 β-cyano-L-Alanine (Standard) [CAS 6232-19-5]
- QM-0161380-01 α-1,4-N-Acetylglucosaminyltransferase 4
- QM-0143593-01 Ziprasidone amino acid [CAS 1159977-64-6]
Ribociclib succinate [CAS 1374639-75-4]
Ribociclib succinate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.