RIPK2/3-IN-2

RIPK2/3-IN-2 (29) is a dual RIPK2 and RIPK3 inhibitor, with IC50 values of 12 nM and 18 nM, respectively. RIPK2/3-IN-2 (29) induces necroptosis, with an EC50 of 0.16 μM[1].

C23H20FN5O

401.44

FC1=C(NC2=NC=NC3=CC(C4=CC=C(N=C4)N5CCOCC5)=CC=C32)C=CC=C1

RIP kinase

RIPK2; RIPK3

99.67

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature