Ritonavir-d8

Ritonavir-d8 is deuterated labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.

C37H40D8N6O5S2

728.99

O[C@@H](C[C@H](CC1=CC=CC=C1)NC([C@@](NC(N(CC2=CSC(C(C)C)=N2)C)=O)([2H])C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])=O)[C@H](CC3=CC=CC=C3)NC(OCC4=CN=CS4)=O

Apoptosis; HIV; HIV Protease; Isotope-Labeled Compounds; SARS-CoV

10 mM in DMSO

Room temperature