Rivastigmine (tartrate) [CAS 129101-54-8]

Rivastigmine tartrate (ENA 713; SDZ-ENA 713) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM, 4.15 μM, respectively. Rivastigmine tartrate can pass the blood brain barrier (BBB) . Rivastigmine tartrate is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease[1][2].

[129101-54-8]

C18H28N2O8

400.42

O=C(OC1=CC=CC([C@@H](N(C)C)C)=C1)N(CC)C.O=C(O)[C@H](O)[C@@H](O)C(O)=O

Cholinesterase (ChE)

AChE

99.03

H2O : 50 mg/mL (ultrasonic)

4°C (Powder, sealed storage, away from moisture)

Room Temperature

H300, H411

H300, H411