RMC-113 [CAS 2258606-34-5]

RMC-113 is a PIP4K2C and PIKfyve inhibitor with the Ki vaules of 46 nM and 370 nM. RMC-113 reverses SARS-CoV-2-induced impairment of autophagic flux. RMC-113 shows antiviral activity[1].

[2258606-34-5]

C21H15N3O2S

373.43

COC1=C(OC)C=CC(C2=CC3=NSC(C#CC4=CC=CN=C4)=C3N=C2)=C1

Autophagy; Dengue Virus; DNA/RNA Synthesis; Filovirus; PIKfyve; SARS-CoV

99.54

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature