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SKU:QM-0155325-01
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Ro 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. Ro 46-8443 displays an at least 100-fold selectivity for ETB (IC50: 34-69 nM) over ETA receptors (IC50: 6800 nM) [1][2].
[175556-12-4]
C31H35N3O8S
609.69
O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=NC(C3=CC=C(OC)C=C3)=NC(OC[C@H](O)CO)=C2OC4=CC=CC=C4OC)=O
Endothelin Receptor
ETA; ETB
98.93
DMSO : 250 mg/mL (ultrasonic)
4°C (Powder, sealed storage, away from moisture)
Room Temperature
H302-H315-H319-H335
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Ro 46-8443 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.