Rodin-C [CAS 2065162-16-3]

Rodin-C is a selective HDAC inhibitor with IC50s of 0.059, 0.18 and 5.39 μM for HDAC1, HDAC2 and HDAC11, respectively, over HDAC3-10. Rodin-C significantly inhibits the HDAC-CoREST complex with low hematological toxicity. Rodin-C can be used for neurologic disorders such as Alzheimer’s disease research[1].

[2065162-16-3]

C18H17FN6O

352.37

O=C(N1CC2=NN(C)C=C2C1)NC3=NC(C4=CC=C(F)C=C4)=CC=C3N

HDAC

HDAC1; HDAC10; HDAC11; HDAC2; HDAC3; HDAC4; HDAC5; HDAC6; HDAC7; HDAC8; HDAC9

Room temperature