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Roflumilast-d4 N-Oxide [CAS 1794760-31-8]
Roflumilast-d4 N-Oxide [CAS 1794760-31-8]
SKU:QM-0151479-01
£200.66 GBP
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Product Details
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Description
Roflumilast-d4 N-Oxide is the deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells[1][2].
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CAS Number
[1794760-31-8]
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Molecular Formula
C17H10D4Cl2F2N2O4
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Molecular Weight
423.23
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Smiles
[2H]C1([2H])C([2H])([2H])C1COC2=C(C=CC(C(NC3=C(Cl)C=[N+]([O-])C=C3Cl)=O)=C2)OC(F)F
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Target
Phosphodiesterase (PDE) ; RSV
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Purity
98.13
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Solubility
10 mM in DMSO|H2O : 0.1mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Roflumilast-d4 N-Oxide [CAS 1794760-31-8]
Roflumilast-d4 N-Oxide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.