Roxatidine [CAS 78273-80-0]

Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is an orally active histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect. Roxatidine is promising for research of gastric and duodenal ulcers[1][2][3].

[78273-80-0]

C17H26N2O3

306.41

O=C(NCCCOC1=CC=CC(CN2CCCCC2)=C1)CO

Caspase; Histamine Receptor; NF-κB; p38 MAPK

H2 Receptor

98.25

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302

H302