Roxithromycin [CAS 80214-83-1]

Roxithromycin (RU-28965) is an orally active semi-synthethic macrolide antibiotic. Roxithromycin inhibits protein biosynthesis in the elongation step by binding to 50S bacterial ribosome. Roxithromycin has antimicrobial, antiproliferative, anti-inflammatory, tumour vasculature inhibiting and lung injury ameliorating effects[1][2][3][4][5][6][7][8][9][10][11].

[80214-83-1]

C41H76N2O15

837.05

C[C@H]([C@H]([C@](O)(C[C@H](/C1=N\OCOCCOC)C)C)O[C@@](O[C@H](C)C[C@@H]2N(C)C)([H])[C@@H]2O)[C@]([C@H](C(O[C@@H]([C@@](O)([C@H](O)[C@H]1C)C)CC)=O)C)([H])O[C@@](O[C@@H](C)[C@@H]3O)([H])C[C@@]3(C)OC

Antibiotic; Apoptosis; Bacterial; NF-κB; p38 MAPK

Macrolide

99.86

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H410

H410