RP101442 [CAS 1306761-08-9]

RP101442, an active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively[1].

[1306761-08-9]

C23H22N4O3

402.45

CC(N[C@H]1CCC2=C1C=CC=C2C3=NOC(C4=CC=C(OC(C)C)C(C#N)=C4)=N3)=O

Drug Metabolite; LPL Receptor

S1PR1; S1PR5

10 mM in DMSO

Room temperature