RSK-IN-2 [CAS 3011713-80-4]

RSK-IN-2 (Compound 3e) is a RSK inhibitor, with IC50 s of 37.89 nM (RSK2), 30.78 nM (RSK1), 20.51 nM (RSK3), 91.28 nM (RSK4) . RSK-IN-2 inhibits tumor cell proliferation, induces apoptosis and causes cell cycle arrest in the G2/M phase[1].

[3011713-80-4]

C25H30ClN7O3

512

CN1CCN(C2=CC(OC)=C(NC3=NC(NC4=CC=CC=C4C(NCCO)=O)=C(Cl)C=N3)C=C2)CC1

Apoptosis; Ribosomal S6 Kinase (RSK)

RSK2; RSK3; RSK4

99.32

DMSO : 35 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature