RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide

RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide is a drug-linker conjugate for ADC. RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide consists of a GPX4 inhibitor and ferroptosis inducer (RSL3-NH2) and a linker (H-Ala-Val-OH) (HY-P4955). RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide can be used for synthesis of ADCs[1].

C69H81ClN12O15

1353.91

O=C(N[C@H](C(N[C@H](C(NC1=CC=C([C@H]2C(NC3=CC=CC=C34)=C4C[C@@H](N2C(CCl)=O)C(OC)=O)C=C1)=O)C)=O)C(C)C)CCCN5N=NC6=C5C7=CC=CC=C7CN(C8=CC=CC=C86)C(CCNC(CCOCCOCCOCCOCCNC(CCN9C(C=CC9=O)=O)=O)=O)=O

Drug-Linker Conjugates for ADC; Ferroptosis; Glutathione Peroxidase

GPX4

Room temperature